Sarah’s general research interest lies in understanding cellular signaling outcomes at the chromatin level. In the Fischle lab, she is studying how alterations in nuclear phospholipid concentrations, specifically in phosphatidylinositol 5-phosphate (PI5P), affect chromatin structure, function and transcriptional output. Sarah is using a variety of cell and molecular biology, imaging and NGS techniques to alter nuclear PI5P levels and study its effects on chromatin.
Diplom in Human Biology, University of Greifswald, Germany
PhD, University of Leeds, UK
After finishing her PhD at the University of Leeds, Sarah joined the Fischle lab at the MPI-BPC in Goettingen in January 2015. In September 2015, she transferred to KAUST to help set up the new Fischle lab and continue to solve fundamental questions of chromatin biology in cell culture models.