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Total result(s) found: 82
  • Kreuz S. and Fischle W. (2016) Oxidative stress signaling to chromatin in health and disease. Epigenomics. 8(6): 843-62. doi: 10.2217/epi-2016-0002.​​​
Keywords:
DNA methylation; RNS; ROS; cancer; diabetes; histone acetylation; histone methylation; oxidative stress
  • ​Hiragami-Hamada K, Soeroes S, Nikolov M, Wilkins B, Kreuz S, Chen C, De La Rosa-Velázquez IA, Zenn HM, Kost N, Pohl W, Chernev A, Schwarzer D, Jenuwein T, Lorincz M, Zimmermann B, Walla PJ, Neumann H, Baubec T, Urlaub H, Fischle W. (2016) Dynamic and flexible H3K9me3 bridging via HP1β dimerization establishes a plastic state of condensed chromatin. Nat Commun. 19;7:11310. doi: 10.1038/ncomms11310
Keywords:
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  • Stützer, A., Liokatis S., Kiesel A., Schwarzer D., Sprangers R., Söding J., Selenko P., and Fischle W. (2016) Modulations of DNA Contacts by Linker Histones and Post-translational Modifications Determine the Mobility and Modifiability of Nucleosomal H3 Tails. Molecular Cell 61(2):247-259.

Keywords:
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  • Zhao H., Ghirlando R., Alfonso C., Arisaka F., Attali I., Bain D.L., Bakhtina M.M., Becker D.F., Bedwell G.J., Bekdemir A., Besong T.M., Birck C., Brautigam C.A., Brennerman W., Byron O., Bzowska A., Chaires J.B., Chaton C.T., Cölfen H., Connaghan K.D., Crowley K.A., Curth U., Daviter T., Dean W.L., Díez A.I., Ebel C., Eckert D.M., Eisele L.E., Eisenstein E., England P., Escalante C., Fagan J.A., Fairman R., Finn R.M., Fischle W., de la Torre J.G., Gor J., Gustafsson H., Hall D., Harding S.E., Cifre J.G., Herr A.B., Howell E.E., Isaac R.S., Jao S.C., Jose D., Kim S.J., Kokona B., Kornblatt J.A., Kosek D., Krayukhina E., Krzizike D., Kusznir E.A., Kwon H., Larson A., Laue T.M., Le Roy A., Leech A.P., Lilie H., Luger K., Luque-Ortega J.R., Ma J., May C.A., Maynard E.L., Modrak-Wojcik A., Mok Y.F., Mücke N., Nagel-Steger L., Narlikar G.J., Noda M., Nourse A., Obsil T., Park C.K., Park J.K., Pawelek P.D., Perdue E.E., Perkins S.J., Perugini M.A., Peterson C.L., Peverelli M.G., Piszczek G., Prag G., Prevelige P.E., Raynal B.D., Rezabkova L., Richter K., Ringel A.E., Rosenberg R., Rowe A.J., Rufer A.C., Scott D.J., Seravalli J.G., Solovyova A.S., Song R., Staunton D., Stoddard C., Stott K., Strauss H.M., Streicher W.W., Sumida J.P., Swygert S.G., Szczepanowski R.H., Tessmer I., Toth R.T. 4th, Tripathy A., Uchiyama S., Uebel S.F., Unzai S., Gruber A.V., von Hippel P.H., Wandrey C., Wang S.H., Weitzel S.E., Wielgus-Kutrowska B., Wolberger C., Wolff M., Wright E., Wu Y.S., Wubben J.M., Schuck P.  (2015) A Multilaboratory Comparison of Calibration Accuracy and the Performance of External References in Analytical Ultracentrifugation. PLoS One 10:e0126420
Keywords:
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  • Tauber M. and Fischle W. (2015) Conserved linker regions and their regulation determine multiple chromatin-binding modes of UHRF1. Nucleus, 6:123-132
Keywords:
DNA methylation; UHRF1; allosteric; chromatin; cooperative; domains; epigenetic; histone; modifications; multiple protein conformations; multivalent
  • Stijf-Bultsma Y., Sommer L., Tauber M., Giardoglou P., Jones D.R., Gelato K.A., Baalbaki M., Hart D., van Pelt J., Shah Z., Rahnamoun H., Toma C., Lauberth S.M., Haramis A.-P., Fischle W. and Divecha N. (2015) The basal transcription complex component TAF3 transduces changes in nuclear PI into transcriptional regulation. Molecular Cell 58:453-467
Keywords:
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  • Fischle W., Schwarzer, D. and Mootz, H.D. (2015) Chemical biology: Chromatin chemistry goes cellular. Nature Chemistry, 7:371​-373
Keywords:
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  • Yung P.Y.K., Stützer A., Fischle W., Martinez A.-M. and Cavalli G. (2015). Histone H3 Serine 28 is essential for efficient Polycomb-mediated gene repression in Drosophila. Cell Reports 11:1437-1445​​
Keywords:
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  • Kost N., Kaiser S., Ostwal Y., Riedel D., Stützer A., Nikolov M., Rathke C., Renkawitz-Pohl R. and Fischle W. (2015) Multimerization of Drosophila sperm protein Mst77F causes a unique condensed chromatin structure. Nucleic Acids Research 43:3033-3045
Keywords:
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  • Fischle W., Mootz, H.D. and Schwarzer D. (2015) Synthetic histone code. Current Opinion in Chemical Biology, 28:131-140​​​​​​
Keywords:
Chromatin
  • Hiragami-Hamada K. and Fischle W. (2014) RNAs – physical and functional modulators of chromatin reader proteins. Biochimica et Biophysica Acta 1839:737-742​​
Keywords:
Chromodomain protein; Epigenetics; Histone modification; Nascent transcript; Non-coding RNA
  • Ferrari K.J., Scelfo A., Jammula S., Cuomo A., Barozzi I., Stützer A., Fischle W., Bonaldi T. and Pasini D. (2014) Polycomb-dependent H3K27me1 and H3K27me2 regulate active transcription and enhancer fidelity. Molecular Cell 53:49-62​​
Keywords:
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  • Wilkins B.J., Rall N.A., Ostwal Y., Kruitwagen T., Hiragami-Hamada K., Winkler M., Barral Y., Fischle W. and Neumann H. (2014) A cascade of histone modifications induces chromatin condensation in mitosis. Science 343:77-80​​
Keywords:
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  • Munari F., Gajda M.J., Hiragami-Hamada K., Fischle W. and Zweckstetter M. (2014) Characterization of the effects of phosphorylation by CK2 on the structure and binding properties of human HP1β.  FEBS Letters 588:1094-1099
Keywords:
Chromo domain; Chromoshadow; Heterochromatin Protein 1; NMR; Phosphorylation; Structure
  • Fischle W. Molecular mechanisms of histone modification function. (2014) Biochimica et Biophysica Acta 1839:621-622 ​   ​
Keywords:
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  • Alpatov R., Lesch B.J., Kinoshita M., Stützer A., Armache K.J., Simon M.D. Wang A., Vakoc C.R., Kingston R.E., Fischle W., Page D.C., Warren S.T. and Shi Y. (2014). A chromatin-dependent role of the fragile X mental retardation protein, FMRP, in the DNA damage response. Cell  157:869-881​
Keywords:
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  • Gelato K.A., Tauber M., Ong M., Winter S., Hiragami-Hamada K., Sindlinger J., Lemak A., Bultsma Y., Houliston S., Schwarzer D., Divecha N., Arrowsmith C.H.  and Fischle W. (2014) Accessibility of different histone H3-binding domains of UHRF1 is allosterically regulated by phosphatidylinositol 5-phosphate. Molecular Cell 54:905-919
Keywords:
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  • Nishibuchi G., Machida S., Osakabe A., Murakoshi H., Hiragami-Hamada K., Nakagawa R., Fischle W., Nishimura Y., Kurumizaka H., Tagami H. and Nakayama J. (2014) N-terminal phosphorylation of HP1α increases its nucleosome-binding specificity. Nucleic Acids Research 42:12498-12511​​
Keywords:
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  • Klingberg R., Jost J.O., Schümann M., Gelato K.A., Fischle W., Krause E. and Schwarzer D. (2014) Analysis of Phosphorylation-Dependent Protein-Protein Interactions of Histone H3. ACS Chemical Biology 10:138-145
Keywords:
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  • Munari F., Rezaei-Ghaleh N., Xiang S., Becker S., Fischle W. and Zweckstetter M. (2013) SStructural plasticity in human heterochromatin protein 1β. PLoS One 8:e60887
Keywords:
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  • Wirth M., Karaca S., Wenzel D., Ho L., Tishkoff D., Lombard D.B., Verdin E., Urlaub H., Jedrusik-Bode M. and Fischle W. (2013) Mitochondrial SIRT4-type proteins in C. elegans and mammals interact with pyruvate carboxylase and other acetylated biotin-dependent carboxylases. Mitochondrion 13:705-720
Keywords:
Biotin-dependent carboxylase; C. elegans; Protein acetylation; Pyruvate carboxylase; SIRT4; Sirtuins
  • Shema-Yaacoby E., Nikolov M., Haj-Yahya M., Siman P., Allemand E., Yamaguchi Y., Muchardt C., Urlaub H., Brik A., Oren M. and Fischle W. (2013) Systematic identification of proteins binding to chromatin-embedded ubiquitylated H2B reveals recruitment of SWI/SNF to regulate transcription. Cell Reports 4:601-608
Keywords:
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  • Siman P., Karthikeyan S.V., Nikolov M., Fischle W. and Brik A. (2013) Convergent chemical synthesis of histone H2B protein for the site-specific ubiquitination at Lys34. Angewandte Chemie International Edition 52:8059-8063​​​
Keywords:
H2B protein; chromatin; peptide ligation; proteins; ubiquitination
  • Sun X.-J., Wang Z., Wang L., Jiang Y., Kost N., Soong T.D., Chen W.-Y., Tang Z., Nakadai T., Elemento O., Fischle W., Melnick A., Patel D.J., Nimer S.D. and Roeder R.G. (2013). A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis. Nature 500:93-97​​
Keywords:
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  • Lang D., Schümann M., Gelato K., Fischle W., Schwarzer D. and Krause E. (2013) Probing the acetylation code of histone H4. Proteomics 13:2989-299​7​​
Keywords:
Cell biology; Chromatin; Histone acetylation; Interactome analysis; Quantitative mass spectrometry; SILAC
  • Seeliger D., Soeroes S., Klingberg R., Schwarzer D., Grubmüller H. and Fischle W. (2012) Quantitative Assessment of Protein Interaction with Methyl-Lysine Analogues by Hybrid Computational and Experimental Approaches. ACS Chemical Biology 7:150-154
Keywords:
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  • Nikolov M. and Fischle W. (2012) Systematic analysis of histone modification readout. Molecular BioSystems 9:182-194
Keywords:
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  • Fischle W. (2012) One, two, three – how histone methylation is read. Epigenomics 4:641-653
Keywords:
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  • van Rossum B., Fischle W. and Selenko P. (2012) Asymmetrically modified nucleosomes expand the histone code. Nature Structural and Molecular Biology 11:1064-1066​
Keywords:
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  • Honda S., Lewis Z.A., Shimada K., Fischle W., Sack R., and Selker E.U. (2012) HP1 forms distinct complexes to direct histone deacetylation and DNA methylation. Nature Structural and Molecular Biology, 19:471-477
Keywords:
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  • Liokatis S., Stützer A., Elsässer S.J., Theillet F.-X., Klingberg R., van Rossum B., Schwarzer D., Allis C.D., Fischle W. and Selenko P. (2012) Phosphorylation of histone H3 Serine 10 establishes a hierarchy for subsequent intramolecular modification events. Nature Structural and Molecular Biology 19:819-823
Keywords:
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  • Munari F., Soeroes S., Zenn H.M., Schomburg A., Kost N., Schroeder S., Klingberg R., Rezaei-Ghaleh N., Stuetzer A., Gelato K.A., Walla P.J., Becker S., Schwarzer D., Zimmermann B., Fischle W.* and Zweckstetter M.* (2012) Methylation of K9 in histone H3 directs alternative modes of highly dynamic interaction of heterochromatin protein hHP1β with the nucleosome. Journal of Biological Chemistry 287:33756-33765, *co-corresponding authors
Keywords:
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  • Mosch K., Franz H., Soeroes S., Singh P.B. and Fischle W. (2011) HP1 recruits activity-dependent neuroprotective protein to H3K9me3 marked pericentromeric heterochromatin for silencing of major satellite repeats. PLoS One 6:e15894
Keywords:
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  • Koester-Eiserfunke N. and Fischle W. (2011) H3K9me2/3 Binding of the MBT Domain Protein LIN-61 Is Essential for Caenorhabditis elegans Vulva Development. PLoS Genetics 7:e1002017
Keywords:
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  • Jeltsch A. and Fischle W. (2011) Molecular epigenetics: connecting human biology and disease with little marks. Chembiochem 12:183-184​
Keywords:
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  • Schmitges F.W., Prusty A.B., Faty M., Stuetzer A., Lingaraju G.M., Aiwazian J., Sack R., Hess D., Li L., Zhou S., Bunker R.D., Wirth U., Bouwmeester T., Bauer A., Ly-Hartig N., Zhao K., Chan H., Gu J., Gut H., Fischle W., Mueller J. and Thoma N.H. (2011) Histone Methylation by PRC2 Is Inhibited by Active Chromatin Marks. Molecular Cell 42:330-341
Keywords:
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  • Oppikofer M., Kueng S., Martino F. Soeroes S., Hancock S.M., Chin J.W., Fischle W. and Gasser S.M. (2011) A dual role of H4K16 acetylation in the establishment of yeast silent chromatin. EMBO Journal 30:2610-2621
Keywords:
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  • Nikolov M., Stützer A., Mosch K., Krasauskas A., Soeroes S., Stark H., Urlaub H. and Fischle W. (2011) Chromatin Affinity Purification and Quantitative Mass Spectrometry Defining the Interactome of Histone Modification Patterns. Molecular and Cellular Proteomics 10:M110.005371
Keywords:
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  • Stojic L.,  Jasencakova Z.,  Prezioso C., Stützer A., Bodega B., Pasini D., Klingberg R., Mozzetta C., Margueron R., Puri P.L., Schwarzer D., Helin K, Fischle W. and Orlando V. (2011) Chromatin regulated interchange between PRC2-Ezh2 and PRC2-Ezh1 complexes controls Myogenin activation in skeletal muscle cells. Epigenetics Chromatin, 4:16
Keywords:
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  • Grote M., Wolf E., Will C.L., Lemm I., Agafonov D.E., Schomburg A., Fischle W., Urlaub H. and Lührmann R. (2010) The Molecular Architecture of the Human Prp19/CDC5L Complex. Molecular and Cellular Biololgy. 30: 2105-2119
Keywords:
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  • Zhang Y., Jurkowska R., Soeroes S., Rajavelu A., Dhayalan A., Bock I., Rathert P., Brandt O., Reinhardt R., Fischle W. and Jeltsch A. (2010) DNA methylation activity of Dnmt3a and Dnmt3a/3L is guided by interaction of the ADD domain with the histone H3 tail. Nucleic Acids Research 38:4246-4253​​
Keywords:
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  • Winter S. and Fischle W. (2010) Epigenetic markers and their cross-talk. Essays in Biochemistry 48: 45-61
Keywords:
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  • Tsai W.-W., Wang Z., Yiu T.T., Akdemir K.C., Xia W., Winter S., Tsai C.-Y., Shi X., Schwarzer D., Plunkett W., Aronow B., Gozani O., Fischle W., Hung M.-C., Patel D.J. and Barton M.C. (2010) TRIM24 links recognition of a non-canonical histone signature to breast cancer. Nature 468:927-932
Keywords:
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  • Wirth M., Paap F., Fischle W., Wenzel D., Agafonov D.E., Samatov T.R., Wisniewski J.R. and Jedrusik-Bode M. (2009) Linker histone HIS-24 and SIR-2.1 deacetylase induce H3K27me3 in C. elegans germline. Molecular and Cellular Biology 29:3700-3709
Keywords:
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  • Fischle W. (2009) Tip60-ing the balance in DSB repair. Nature Cellular Biology 11:1279-1281
Keywords:
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  • Franz H., Mosch K., Soeroes S., Urlaub H. and Fischle W. (2009) Multimerization and H3K9me3 binding is required for CDYL1b heterochromatin association. Journal of Biological Chemistry 284:35049-35059
Keywords:
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  • Zhang K., Mosch K., Fischle W. and Grewal S.I. (2008) Roles of the Clr4 methyltransferase complex in nucleation, spreading and maintenance of heterochromatin. Nature Structural and Molecular Biology 15:381-388
Keywords:
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  • Winter S., Simboeck E., Fischle W., Zupkovitz G., Dohnal I., Mechtler K., Ammerer G. and Seiser C. (2008) 14-3-3 Proteins recognize a histone code at histone H3 and are required for transcriptional activation. EMBO Journal. 27:88-99
Keywords:
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  • Fischle W. (2008) Talk is cheap-cross-talk in establishment, maintenance, and readout of chromatin modifications. Genes and Development 22:3375-3382
Keywords:
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  • Kalakonda N., Fischle W., Boccuni P., Gurvich N., Hoya-Arias R., Zhao X., Miyata Y., Magrogan D., Zhang J., Sims J.K., Rice J.C. and Nimer S.D. (2008) Histone H4 lysine 20 monomethylation promotes transcriptional repression by L3MBTL1. Oncogene 27: 4293-4304
Keywords:
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  • Winter S., Fischle W. and Seiser C. (2008) Modulation of 14-3-3 interaction with phosphorylated histone H3 by combinatorial modification patterns. Cell Cycle 7:1336-1342
Keywords:
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  • Fischle W.*, Franz H., Jacobs S.A., Allis C.D., and Khorasanizadeh S.* (2008) Specificity of the chromodomain Y chromosome family of chromodomains for lysine-methylated ARK(S/T) motifs. Journal of Biological Chemistry 283:19626-19635, *co-corresponding authors
Keywords:
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  • Gelato K.A. and Fischle W. (2008) Role of histone modifications in defining chromatin structure and function. Biological Chemistry 389:353-363
Keywords:
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  • Li H., Fischle W., Wang W., Duncan W.M., Liang L., Murakami-Ishibe S., Allis C.D. and Patel D.J. (2007) Structural basis for lower lysine methylation state-specific readout by MBT repeats of L3MBTL1 and an engineered PHD finger. Molecular Cell 28:677-691
Keywords:
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  • Grimm C., de Ayala Alonso A.G., Rybin V., Steuerwald U., Ly-Hartig N., Fischle W., Mueller J. and Mueller C.W. (2007) Structural and functional analyses of methyl-lysine binding by the malignant brain tumour repeat protein Sex comb on midleg. EMBO Reports 8:1031-1037
Keywords:
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  • Dormann H.L., Tseng B.S., Allis C.D., Funabiki H. and Fischle W. (2006) Dynamic regulation of effector protein binding to histone modifications: The biology of HP1 switching. Cell Cycle 5:2842-2851
Keywords:
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  • Klymenko T., Papp B., Fischle W., Kocher T., Schelder M., Fritsch C., Wild B., Wilm M. and Mueller J. (2006) A Polycomb group protein complex with sequence-specific DNA-binding and selective methyl-lysine-binding activities. Genes and Development 20:1110-1122
Keywords:
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  • Yamada T., Fischle W., Sugiyama T., Allis C.D. and Grewal S.I. (2005) The nucleation and maintenance of heterochromatin by a histone deacetylase in fission yeast. Molecular Cell 20:173-185
Keywords:
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  • Fischle W. (2005) In nucleo enzymatic assays for the identification and characterization of histone modifying activities. Methods 36:362-367
Keywords:
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  • Fischle W.*, Tseng B.S., Dormann H.L., Ueberheide B.M., Garcia B.A., Shabanowitz J., Hunt D.F., Funabiki H.*  and Allis C.D. (2005) Regulation of HP1-chromatin binding by histone H3 methylation and phosphorylation. Nature 438:1116-1122, *co-corresponding authors
Keywords:
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  • Verdin E., Dequiedt F., Fischle W., Frye R., Marshall B. and North B. (2004) Measurement of mammalian histone deacetylase activity. Methods in Enzymology Vol 377:180-196​
Keywords:
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  • Jacobs S.A., Fischle W. and Khorasanizadeh S. (2004) Assays for structure and dynamics of chromodomain interactions with histone peptides. Methods in Enzymology Vol 376:131-148​
Keywords:
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  • Wang Y., Fischle W., Cheung W., Jacobs S.A., Khorasanizadeh S. and Allis C.D. (2004) Beyond the double helix: Writing and reading the histone code. In: Reversible protein Acetylation. Novartis Found. Symp. 259:3-17, Wiley, Chichester
Keywords:
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  • Fischle W., Wang Y. and Allis C.D. (2003) Binary switches and modification cassettes in histone biology and beyond. Nature 425:475-479
Keywords:
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  • Dequiedt F., Kasler H., Fischle W., Kiermer V., Weinstein M., Herndier B. and Verdin E. (2003) Regulation of Nur77 transcription by HDAC7, a thymus-specific histone deacetylase. Immunity 18:687-698
Keywords:
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  • Fischle W., Wang Y. and Allis C.D. (2003) Histone and chromatin cross-talk. Current Opinion in Cell Biology 15:172-183
Keywords:
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  • Fischle W., Wang Y., Jacobs S.A., Kim Y., Allis C.D. and Khorasanizadeh S. (2003) Molecular basis for the discrimination of repressive methyl-lysine marks in histone H3 by Polycomb and HP1 chromodomains. Genes and Development 19:1870-1881
Keywords:
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  • Fischle W., Dequiedt F., Hendzel M., Guenther M.G., Lazar M.A., Voelter W. and Verdin E. (2002) Enzymatic activity associated with class II HDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR. Molecular Cell 9:45-57
Keywords:
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  • Murphy J.C., Fischle W., Verdin E. and Sinclair J.H (2002). Control of cytomegalovirus lytic gene expression by histone acetylation. EMBO Journal 21:1112-1120
Keywords:
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  • Fischle W., Dequiedt F., Fillion M., Hendzel M.J., Voelter W. and Verdin E. Human HDAC7 histone deacetylase activity is associated with HDAC3 in vivo (2001). Journal of Biological Chemistry 276:35826-35835
Keywords:
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  • Fischle W., Kiermer V., Dequiedt F. and Verdin E. (2001) The emerging role of class II histone deacetylases. Biochemistry and Cell Biology 79:337-348
Keywords:
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  • Kruhlak M.J., Hendzel M.J., Fischle W., Bertos N.R., Hameed S., Yang X.J., Verdin E. and Bazett-Jones D.P. (2001) Regulation of global acetylation in mitosis through loss of histone acetyltransferases and deacetylases from chromatin. Journal of Biological Chemistry 276:38307-38319
Keywords:
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  • Chen Lf, Fischle W., Verdin E. and Greene W.C. (2001) Duration of nuclear NF-kappaB action regulated by reversible acetylation. Science 293:1653-1657
Keywords:
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  • Tenidis K., Waldner M., Bernhagen J., Fischle W., Bergmann M., Weber M., Merkle M.L., Voelter W., Brunner H. and Kapurniotu A. (2000) Identification of a penta- and hexapeptide of islet amyloid polypeptide (IAPP) with amyloidogenic and cytotoxic properties. Journal of Molecular Biology 295:1055-1071
Keywords:
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  • Guenther M.G., Lane W.S., Fischle W., Verdin E., Lazar M.A. and Shiekhattar R. (2000) Histone deacetylase 3 and a WD40 repeat protein linked to deafness are components of a core SMRT corepressor complex. Genes and Development 14:1048-1057
Keywords:
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  • Huynh K.D., Fischle W., Verdin E. and Bardwell V.J. (2000) BCoR, a novel co-repressor involved in BCL-6 repression. Genes and Development 14:1810-1823​
Keywords:
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  • Kruhlak M.J., Levert M.A., Fischle W., Verdin E., Bazett-Jones D.P. and Hendzel M.J. (2000) Reduced Mobility of the Alternate Splicing Factor (Asf) through the Nucleoplasm and Steady State Speckle Compartments. Journal of Cellular Biology 150:41-51​
Keywords:
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  • Fischle W., Emiliani S., Hendzel M.J., Nagase T., Nomura N., Voelter W. and Verdin E. (1999) A new family of human histone deacetylases related to Saccharomyces cerevisiae, HDA1p. Journal of Biological Chemistry 274:11713-11720
Keywords:
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  • Ott M., Schnolzer M., Garnica J., Fischle W., Emiliani S., Rackwitz H.-R. and Verdin E. (1999) Acetylation of the HIV-1 Tat protein by p300 is important for its transcriptional activity. Current Biology 9:1489-1492
Keywords:
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  • Emiliani S., Van Lint C., Fischle W., Paras Jr. P., Ott M., Brady J. and Verdin E. (1996) A point mutation in the HIV-1 tat responsive element is associated with postintegration latency. Proceedings of the National Academy of Sciences U.S.A. 93:6377-6381
Keywords:
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  • Emiliani S., Fischle W., Ott M., Van Lint C., Amella C.A. and Verdin E. (1998) Mutations in the tat gene are responsible for human immunodeficiency virus type 1 postintegration latency in the U1 cell line. Journal of Virology 72:1666-1670
Keywords:
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  • Emiliani S., Fischle W., Van Lint C., Al-Abed Y. and Verdin E. (1998) Characterization of a human RPD3 ortholog, HDAC3. Proceedings of the National Academy of Sciences U.S.A. 95:2795-2800
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